2/26/03 4:30, DL480.   

Prof. Cline will be speaking about disciplined approach to software development.

Alan Cline is President of Carolla Development, a consulting company that helps other companies improve their software development processes. He teaches capstone project management and development courses for OSU’s Computer Science department. He has 30 years of experience in the computing industry, from IBM mainframes to Windows NT and Unix. During his profession, he has increasingly been more involved in zero-defect software development, process engineering, the Software Engineering Institute’s CMM, and Kent Beck’s Extreme Programming (XP) techniques. Since developing the Carolla Methodology, over 60% of Mr. Cline’s projects have been completed with zero defects, on time predictably. His last project, as a member of a three-person steering team, reduced $31 million from his client’s IT budget. He has been published several times, and speaks to professional groups regularly. Pictures from Prof. Cline's presentation

The next meeting is scheduled for: 3/5/03 4:30 DL 480   

Computer Analysis and Generation of RLGS Profiles

Restricted Landmark Genomic Scanning (RLGS) is a two-dimensional gel electrophoresis method for detecting DNA changes caused by human cancers. Genomic DNA is split into subsequences using enzymes, which are then spread out on a two dimensional gel. The gel is dried and exposed to X-ray film, resulting in an ``RLGS profile'' of approximately 2000 spots. DNA sequences correspond to spots on this gel while DNA changes correspond to added, missing or amplified spots. Such spot changes can be used to identify and diagnose human cancers. We'll discuss current OSU research on automating RLGS profile analysis and on computer generation of "virtual" RLGS profiles. This work is in collaboration with Drs. Christoff Plass and Dominic Smiraglia from the OSU Department of Human Cancer Genetics and with Dr. Ilya Ioschikhes from OSU Department of Biomedical Informatics. Dr. Wenger is a an associate professor in the OSU Dept. of Computer and Information Science who works in geometric algorithms, computer graphics and visualization.